- Trials with a EudraCT protocol (9)
- Paediatric studies in scope of Art45 of the Paediatric Regulation (0)
9 result(s) found for: Viral Vectors.
Displaying page 1 of 1.
EudraCT Number: 2022-001092-14 | Sponsor Protocol Number: TIGEM5_USH | Start Date*: 2023-10-12 | ||||||||||||||||
Sponsor Name:FONDAZIONE TELETHON | ||||||||||||||||||
Full Title: A phase I/II open label, dose escalation study of sub-retinal administration of a “mixture of two adeno-associated viral vectors of serotype 8 containing the 5 ´- half sequence of the human MYO7A ... | ||||||||||||||||||
Medical condition: Usher syndrome (USH) is characterized by the association of sensorineural hearing loss, Retinitis Pigmentosa (RP), and, in some cases, vestibular dysfunction. It is the most frequent cause of deaf-... | ||||||||||||||||||
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Population Age: Children, Adolescents, Under 18, Adults | Gender: Male, Female | |||||||||||||||||
Trial protocol: IT (Ongoing) | ||||||||||||||||||
Trial results: (No results available) |
EudraCT Number: 2016-004867-38 | Sponsor Protocol Number: AUTO-LT1 | Start Date*: 2018-05-18 |
Sponsor Name:Autolus Limited | ||
Full Title: Long-term follow-up of patients previously treated with autologous T cells genetically modified with viral vectors. | ||
Medical condition: Potential malignancy in patients who received treatment with Autolus' CAR T cell therapy. | ||
Disease: | ||
Population Age: Infants and toddlers, Children, Adolescents, Under 18, Adults, Elderly | Gender: Male, Female | |
Trial protocol: GB (GB - no longer in EU/EEA) NL (Ongoing) | ||
Trial results: (No results available) |
EudraCT Number: 2015-001383-18 | Sponsor Protocol Number: | Start Date*: 2015-11-30 | |||||||||||
Sponsor Name:University of Oxford | |||||||||||||
Full Title: An open label Phase 2 clinical trial of retinal gene therapy for choroideremia using an adeno-associated viral vector (AAV2) encoding Rab-escort protein 1 (REP1) | |||||||||||||
Medical condition: Choroideremia - a currently incurable retinal degeneration caused by null mutations in the CHM gene encoding REP1 protein located on the X chromosome. The condition causes blindness in males by the... | |||||||||||||
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Population Age: Adults | Gender: Male | ||||||||||||
Trial protocol: GB (GB - no longer in EU/EEA) | |||||||||||||
Trial results: View results |
EudraCT Number: 2011-005477-24 | Sponsor Protocol Number: VAC045 | Start Date*: 2012-02-28 |
Sponsor Name:University of Oxford | ||
Full Title: A Phase I/IIa Sporozoite Challenge Study to Assess the Protective Efficacy of Two Prime-boost Malaria Vaccine Candidates: ChAd63 and MVA encoding ME-TRAP and the same Viral Vectors encoding CS | ||
Medical condition: Plasmodium falciparum infection | ||
Disease: | ||
Population Age: Adults | Gender: Male, Female | |
Trial protocol: GB (Completed) | ||
Trial results: View results |
EudraCT Number: 2016-000925-38 | Sponsor Protocol Number: UCL13/0076 | Start Date*: 2017-01-04 | ||||||||||||||||
Sponsor Name:University College London (UCL) | ||||||||||||||||||
Full Title: GO-8: Gene therapy for haemophilia A using a novel serotype 8 capsid pseudotyped adeno-associated viral vector encoding Factor VIII-V3 | ||||||||||||||||||
Medical condition: Severe Haemophilia A | ||||||||||||||||||
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Population Age: Adults, Elderly | Gender: Male | |||||||||||||||||
Trial protocol: GB (GB - no longer in EU/EEA) | ||||||||||||||||||
Trial results: (No results available) |
EudraCT Number: 2010-019962-10 | Sponsor Protocol Number: P1-SAF301 | Start Date*: Information not available in EudraCT | |||||||||||
Sponsor Name:SANFILIPPO Therapeutics SAS | |||||||||||||
Full Title: AN OPEN-LABEL, SINGLE ARM, MONOCENTRIC, PHASE I/II CLINICAL STUDY OF INTRACEREBRAL ADMINISTRATION OF ADENO-ASSOCIATED VIRAL VECTORS SEROTYPE 10 CARRYING THE HUMAN SGSH AND SUMF1 cDNAS FOR THE TREAT... | |||||||||||||
Medical condition: Sanfilippo type A syndrome (also named Mucopolysaccharidosis Type A) | |||||||||||||
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Population Age: Infants and toddlers, Children, Under 18 | Gender: Male, Female | ||||||||||||
Trial protocol: FR (Completed) | |||||||||||||
Trial results: (No results available) |
EudraCT Number: 2012-004416-66 | Sponsor Protocol Number: VAC052 | Start Date*: 2012-11-26 |
Sponsor Name:University of Oxford | ||
Full Title: A Phase I/IIa Sporozoite Challenge Study to Assess the Efficacy of Candidate Combination Malaria Vaccine Approaches using the ChAd63 and MVA vectors encoding the antigens ME-TRAP, CS and AMA1. | ||
Medical condition: Plasmodium falciparum Infection | ||
Disease: | ||
Population Age: Adults | Gender: Male, Female | |
Trial protocol: GB (Completed) | ||
Trial results: View results |
EudraCT Number: 2014-001301-40 | Sponsor Protocol Number: VAC059 | Start Date*: 2014-07-31 |
Sponsor Name:University of Oxford | ||
Full Title: A Phase I/IIa Sporozoite Challenge Study to Assess the Safety and Protective Efficacy of Concomitant Administration of the Combination Malaria Vaccine Candidate Regimen of RTS,S/AS01¬B + ChAd63 and... | ||
Medical condition: Plasmodium falciparum infection | ||
Disease: | ||
Population Age: Adults | Gender: Male, Female | |
Trial protocol: GB (Prematurely Ended) | ||
Trial results: View results |
EudraCT Number: 2018-000195-15 | Sponsor Protocol Number: P4-SAF-302 | Start Date*: 2018-12-27 | |||||||||||
Sponsor Name:Lysogene SA | |||||||||||||
Full Title: An Open-Label, Single-Arm, Multicenter Study of Intracerebral Administration of Adeno-Associated Viral Vectors Serotype rh10 Carrying the Human N-sulfoglucosamine sulfohydrolase (SGSH) cDNA for the... | |||||||||||||
Medical condition: Mucopolysaccharidosis Type IIIA | |||||||||||||
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Population Age: Infants and toddlers, Children, Under 18 | Gender: Male, Female | ||||||||||||
Trial protocol: FR (Ongoing) GB (GB - no longer in EU/EEA) NL (Temporarily Halted) DE (Temporarily Halted) | |||||||||||||
Trial results: (No results available) |
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